Friday, 1 July 2011

Grocott Hexamine-Silver Special Stain For Fungus – Method and Tips

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The Grocott Hexamine-Silver special stain is the method of choice for a large majority of histopathology laboratories for the demonstratio...
Thursday, 30 June 2011

Perls’ Technique For The Demonstration of Haemosiderin – Method and Tips

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Iron is absorbed in the duodenum by cells called enterocytes. It is then stored or combined with a transport protein molecule. This iron-p...
Thursday, 23 June 2011

Modified Ziehl–Neelsen Stain For Leprosy Bacilli – Method and Tips

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Leprosy bacilli in comparison with tubercle bacilli are much less acid- and alcohol-fast. The leprosy bacilli’s lipid envelope is also muc...
Wednesday, 22 June 2011

Lack of UV-A Protection In Daily Moisturising Creams

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Came across another interesting article in the May edition of ‘The Archives of Dermatology’ 2011. The article is entitled ‘Lack of UV-A Pr...
Monday, 20 June 2011

Verhoeff Van Gieson Elastin Special Stain – Method and Tips

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Elastin is a connective tissue protein which allows the tissues of the body to return to their original shape after distortion or stretchi...
Friday, 17 June 2011

Persistent Melanocytic Nevi: A Review and Analysis of 205 cases

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Great article in the June 2011 issue of the ‘Journal of Cutaneous Pathology’ regarding persistent melanocytic naevi.  Good reading for th...
Thursday, 16 June 2011

Melanoma Research – Sex differences in survival of cutaneous melanoma are age dependent

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Came across an interesting article in the latest issue of the Melanoma Research journal regarding differences in survival rates based on s...
Tuesday, 14 June 2011

Periodic-Acid Schiff Diastase (PASD) Special Stain – Method and Tips

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In my previous post I covered the Periodic Acid-Schiff reaction (PAS) special stain which is by far the most common stain performed in a r...
Monday, 13 June 2011

Periodic-Acid Schiff (PAS) Special Stain – Method and Tips

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The Periodic-Acid Schiff (PAS) technique (and its numerous variations) is by far the most commonly performed special stain within the hist...
Friday, 10 June 2011

Alcian Blue Stain For Acidic Mucins – Method and Tips

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The alcian blue stain is this author’s preferred stain for the demonstration of acidic mucins. The dye was originally used for the dyeing ...
Thursday, 9 June 2011

Ziehl–Neelsen Stain For Acid-Fast Organisms – Method and Tips

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The Ziehl–Neelsen (ZN) stain is a common standard stain which is readily performed in a majority of histopathology laboratories around the...
Wednesday, 8 June 2011

Cutaneous Squamous Cell Carcinoma – Overview

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Squamous cell carcinoma (SCC) is defined by the World Health Organisation as ‘a malignant neoplasm of epidermal (and mucous membrane) kera...
Tuesday, 7 June 2011

Superficial Basal Cell Carcinoma – A closer look

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Superficial basal cell carcinoma (SBCC) is a growth pattern of basal cell carcinoma (BCC) which accounts for approximately 10-30% of all B...
Monday, 6 June 2011

Solar Keratosis and Its Histological Subtypes

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Solar keratosis is defined by the World Health Organization as ‘a common intraepidermal neoplasm of sun-damaged skin characterized by vari...
Friday, 3 June 2011

Basal Cell Carcinoma and It’s Histological Growth Types

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Basal cell carcinoma (BCC) is the most common skin malignancy and it’s incidence is on the increase. Below is a description of the four ma...
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Thursday, 2 June 2011

Prognostic Factors of Cutaneous Squamous Cell Carcinoma

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Below is a brief description of the prognostic factors involved with cutaneous squamous cell carcinoma, ie. SCC of the skin. Site The a...
Wednesday, 1 June 2011

Non-melanoma skin cancer (NMSC) treatments

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Below are the most common treatments available, plus a brief description, once a NMSC has been diagnosed (usually a basal cell carcinoma o...
2 comments:
Tuesday, 31 May 2011

Melanoma – Prognostic Factors – Quick Overview

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Listed below are the most important prognostic factors with regard to cutaneous melanoma. AGE – the older the patient, the poorer the pro...
Monday, 30 May 2011

Special Stains for Amyloid - Method and Tips

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Amyloid is a common substance found in the skin, in association with a number of disorders including, lichen amyloidosis, macular amyloido...
Friday, 27 May 2011

Cutaneous Spindle Cell Tumour Immunohistochemistry Panel

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This post is about cutaneous spindle cell tumours and their immunohistochemistry (IHC) profiles. I get many questions from laboratory staf...
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